Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC261H401N65O80S6

DescriptionStandard

        MKKEYELMNTIQEISLEELDQIIGAGKNGVFKTISHECHMNSFQFFFTCCS
    

Molecular Weight5921.75 Da

Isoelectric Point (pI)5.09

Net Charge (pH 7.0)-3.34

Net Charge (pH 7.4) -3.72

Charge Density (pH 7.0) -0.0655

GRAVY Index-0.16

Hydrophobic Moment 0.48

Boman Index0.08

Instability Index24.91

Aliphatic Index 68.82

Aromaticity 0.1176

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2361.24

LogP -21.57

H-bond Donors 82.0

H-bond Acceptors 85.0

Rotatable Bonds 204.0

Heavy Atoms 412.0

Ring Count 8.0

Amide Bonds 56.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106986 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus mitis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear lantibiotic precursor [Linear]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0350772 VERIFIED: NO