MYP_121957
Pituitary adenylate cyclase-activating polypeptide 38
Antimicrobial
Antimicrobial
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Antifungal
Cardiovascular
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Vascular tone modulation
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Vasoactive peptide
Cardiovascular
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Vascular tone modulation
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Vasodilatory activity
Delivery / Targeting
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Barrier transport
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Blood-brain barrier shuttle
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Blood-Brain Barrier
Delivery / Targeting
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Cell penetration
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Cell-penetrating peptide
Delivery / Targeting
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Drug delivery vehicle
Enzyme modulation
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Enzyme inhibition
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ACE inhibition
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ACE inhibitory
Hormonal / Endocrine
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Hormone peptide
Immunology
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Chemokine signaling
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Chemokine-like peptide
Neurological / Signaling
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Neuromodulation
Neurological / Signaling
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Neuropeptide activity
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Neuropeptide
Neurological / Signaling
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Neuropeptide activity
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Neuropeptide signaling
Regulatory peptide
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Biological modulation
Regulatory peptide
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Biological regulation
Regulatory peptide
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Cell-cell communication
Reproductive biology
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Reproductive modulation
Standard
38 amino acids
C203H330N62O54S
Standard
HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK
4535.24 Da
10.41
8.84
8.57
0.2326
-1.06
0.56
-0.35
35.97
61.58
0.1316
5960.00
5960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1964.15
-18.81
72.0
65.0
159.0
320.0
6.0
40.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0342133
VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Glucagon
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Leu27 Amidation
Bio-Activity Profile
Hormone
Metabolic
RECORD: Rec_0363439
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
PACAP
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
D-residue notation at positions 2; Mixed L/D stereochemistry with D-annotated positions 2
Bio-Activity Profile
Neuroprotective
0.0097±0.0025 μM
IC50
DPP IV, in vitro; >14400 s
RECORD: Rec_0378140
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
RECORD: Rec_0391270
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Pituitary adenylate cyclase-activating polypeptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
27:Leucine amide
Bio-Activity Profile
Hormone
Endocrine
Neuropeptide
Neuromodulator
Metabolic regulation
Physiological regulation
Reproductive regulator
Growth regulation
Development regulation
Receptor modulation
ACE inhibitory
its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells
Experimental: 23±6 minutes; /1380 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
RECORD: Rec_0401193
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antifungal
B. velezensis
76 μg/mL
MIC
Showing 5 records on this page · Page 10 of 11