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MYP_121955
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C90H126N20O14
Standard
Sequence
ILPFKFPFFPFRR
Physicochemical Analysis
1712.09 Da
12.00
2.76
2.55
0.2122
0.35
0.46
0.17
145.44
60.00
0.3846
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
535.97
1.70
18.0
17.0
48.0
124.0
8.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0054635 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 53.8%, C 46.2% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiparasitic Antimicrobial Antiplasmodial
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0096693 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Rat erythrocytes
80 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/8849687/ PMID8849687 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8849687/
RECORD: Rec_0096969 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ILF
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium berghei ANKA 2.34 (ookinetes)
50 μM
Microscopy (Phase-contrast by Neubauer hemocytometer)
PMID12069961 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12069961/
RECORD: Rec_0134178 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis IFO 3513
12.5 μg/mL
MIC
PaperStructure-function relationships in the tryptophan-rich, antimicrobial peptide indolicidin. PMID11695650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11695650/
RECORD: Rec_0151007 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ILF
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium yoelii nigeriensis Killick-Kendrick N67(ookinetes)
50 μM
Microscopy (Phase-contrast by Neubauer hemocytometer)
PMID12069961 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12069961/
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