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MYP_121943
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Basic Information
Antimicrobial peptide M
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
31 amino acids
C144H237N39O39S2
Standard
Sequence
ALWKTMLKKLGTMALHAGKAAFGAAADTISQ
Physicochemical Analysis
3202.79 Da
10.00
2.88
2.63
0.0929
0.32
0.51
0.22
6.23
88.71
0.0645
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1246.18
-10.94
44.0
45.0
108.0
224.0
4.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0378886 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli.
PMID10477123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10477123/
RECORD: Rec_0391275 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
38 μM
MIC
PMID10477123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10477123/
RECORD: Rec_0397880 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
38 μM
MIC
PaperAntimicrobial peptides from the Brazilian frog Phyllomedusa distincta.
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