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MYP_121913
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Basic Information
Leucocin A (18-35)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C78H114N26O24
Standard
Sequence
WGEAFSAGVHRLANGGNG
Physicochemical Analysis
1799.90 Da
6.75
-0.15
-0.40
-0.0083
-0.32
0.50
0.17
-15.07
54.44
0.1111
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
808.10
-10.64
28.0
25.0
56.0
128.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0154026 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Salmonella typhimurium CMCC 51005
71.15 μM
MIC
PMID28002968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28002968/
RECORD: Rec_0223844 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
>71.15 μM
Hemolysis
PMID28002968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28002968/
RECORD: Rec_0232134 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
71.15 μM
MIC
PMID28002968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28002968/
RECORD: Rec_0233660 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Listeria monocytogenes 21633
71.15 μM
MIC
PaperInsights into the Antimicrobial Activity and Cytotoxicity of Engineered α-Helical Peptide Amphiphiles PMID28002968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28002968/
RECORD: Rec_0241135 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus 1160
71.15 μM
MIC
PaperInsights into the Antimicrobial Activity and Cytotoxicity of Engineered α-Helical Peptide Amphiphiles PMID28002968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28002968/
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