Peptide Database

Peptide NameBeta-defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC334H554N106O80S7

DescriptionStandard

        MRLHQLLFALLFLFVVPAPGEGGLINAVQRYFCRVRGGRCAALTCLPRETQIGHCSLKGRKCCRRKK
    

Molecular Weight7559.09 Da

Isoelectric Point (pI)10.54

Net Charge (pH 7.0)10.62

Net Charge (pH 7.4) 10.20

Charge Density (pH 7.0) 0.1584

GRAVY Index0.09

Hydrophobic Moment 0.78

Boman Index-0.04

Instability Index27.03

Aliphatic Index 94.63

Aromaticity 0.0746

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3003.97

LogP -26.17

H-bond Donors 114.0

H-bond Acceptors 100.0

Rotatable Bonds 253.0

Heavy Atoms 527.0

Ring Count 10.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363080 VERIFIED: NO

Provenance & Taxonomy

OrganismFukomys damarensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence