Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC341H537N95O93S7

DescriptionStandard

        LCLFHSPLLRSLLLYALRNEFDTDKICGYGTARCRRRCKTGEFFIGTCPNIYPCCLKTWDKGESKVG
    

Molecular Weight7679.95 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.78

Net Charge (pH 7.4) 4.41

Charge Density (pH 7.0) 0.0714

GRAVY Index-0.17

Hydrophobic Moment 0.54

Boman Index-0.04

Instability Index49.86

Aliphatic Index 77.16

Aromaticity 0.1194

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3036.03

LogP -27.16

H-bond Donors 116.0

H-bond Acceptors 106.0

Rotatable Bonds 251.0

Heavy Atoms 536.0

Ring Count 13.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283195 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Tax ID9689

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal