Peptide Database

Peptide NameCecropin A1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC105H176N30O27

DescriptionStandard

        RVFRASEKALPVVTGYKAIGK
    

Molecular Weight2290.71 Da

Isoelectric Point (pI)10.45

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1790

GRAVY Index-0.01

Hydrophobic Moment 0.73

Boman Index-0.02

Instability Index20.87

Aliphatic Index 92.86

Aromaticity 0.0952

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 936.38

LogP -7.67

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 76.0

Heavy Atoms 162.0

Ring Count 3.0

Amide Bonds 20.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0284424 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)