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MYP_121744
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Basic Information
RANATUERIN 3
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
32 amino acids
C154H251N39O42S3
Standard
Sequence
GFLDIINKLGKTFAGHMLDKIKCTIGTCPPSP
Physicochemical Analysis
3417.07 Da
8.82
1.83
1.54
0.0571
0.16
0.71
0.18
47.00
88.44
0.0625
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1270.42
-10.65
44.0
48.0
111.0
238.0
6.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0193391 VERIFIED: YES
Provenance & Taxonomy
Aquarana catesbeiana [Animal]
Ranatuerin
8400
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
23-28
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
60.0 μM
MIC
PaperJ. Goraya et al. / Biochemical and Biophysical Research Communications 250 (1998) 589-592. Ranatuerins: antimicrobial peptides isolated from the skin of the American bullfrog, Rana catesbeiana Evidence URLhttps://www.uniprot.org/uniprotkb/P82780/entry
RECORD: Rec_0202573 VERIFIED: YES
Provenance & Taxonomy
Rana catesbeiana [Animal]
Ranatuerin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
60 μM
MIC
PMID9784389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784389/
RECORD: Rec_0209225 VERIFIED: YES
Provenance & Taxonomy
American bull [Animal]
Ranatuerin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial
PMID9784389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784389/
RECORD: Rec_0344866 VERIFIED: YES
Provenance & Taxonomy
Rana catesbeiana [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
23-28
Disulfide bridge: C23,C28;
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
60 μM
MIC
PaperRanatuerins: antimicrobial peptides isolated from the skin of the American bullfrog, Rana catesbeiana.
RECORD: Rec_0355125 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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