Peptide Database

Peptide NameColicin-B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length470 amino acids

Chemical FormulaC2272H3626N612O695S10

DescriptionStandard

        MPPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAARTVLENGLRGGLPEPSRPAAVPFARLEPASGNEKKIIRLMVTQQLEKVTDIPASQLPAAGNNVPVKYRLTDLMQNGTQYIAIIGGIPMTVPVVDAVPVPDRSRPGTNIKDVYSAPVSPNLPDLVLSVGQMNTPVLSNPEIQEEGVIAETGNYVEAGYTMSSNNHDVIVRFPDGSGVSPLYISTVEILDRNSLSQRQEAENKAKDDFRVKKEQYNDEKAVLTKTSEVIINVGDKAGEYLGDKYRTLSREIAENIRNFQGKTIRSYDEAMSSINKLIENPNLKINATDKEAIVNAWKAFDAKDMGNKFASLGKTFKAADYAIKANNIREKSIEGYQTGNWGPLMLEIESWVLSGIASTVALGLFSTIAGSALLAVGTPPVVVGIMGVFVAAVVGVLIDDKFADVLNNEIIKPAH
    

Molecular Weight50955.43 Da

Isoelectric Point (pI)5.19

Net Charge (pH 7.0)-9.16

Net Charge (pH 7.4) -9.66

Charge Density (pH 7.0) -0.0195

GRAVY Index-0.16

Hydrophobic Moment 0.78

Boman Index0.07

Instability Index39.17

Aliphatic Index 95.40

Aromaticity 0.0660

Extinction Coeff. Reduced 57870.00

Extinction Coeff. Oxidized 57870.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0299502 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli 1-250-04_S3_C2 [Bacterium]

FamilyChannel forming colicin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli