Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC369H576N100O111S11

DescriptionStandard

        MKTFAVAATVSLLLPSLCVHENSAVPVDEARTLLQSPFFHWSAQVDENKMKENEYPGPARCRFCCGCCLADVCGLCCD
    

Molecular Weight8541.84 Da

Isoelectric Point (pI)5.17

Net Charge (pH 7.0)-3.40

Net Charge (pH 7.4) -3.86

Charge Density (pH 7.0) -0.0435

GRAVY Index0.17

Hydrophobic Moment 0.47

Boman Index0.10

Instability Index48.21

Aliphatic Index 76.28

Aromaticity 0.0769

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3330.20

LogP -33.62

H-bond Donors 121.0

H-bond Acceptors 121.0

Rotatable Bonds 271.0

Heavy Atoms 591.0

Ring Count 14.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0349738 VERIFIED: NO

Provenance & Taxonomy

OrganismXiphophorus maculatus [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal