Peptide Database

Peptide NameSLAY-screened peptide P2947

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC89H147N31O31

DescriptionStandard

        SSAEPRNSHNPLNSPRLASL
    

Molecular Weight2147.31 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)0.55

Net Charge (pH 7.4) 0.29

Charge Density (pH 7.0) 0.0275

GRAVY Index-1.00

Hydrophobic Moment 0.46

Boman Index-0.23

Instability Index59.76

Aliphatic Index 68.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1010.05

LogP -15.75

H-bond Donors 34.0

H-bond Acceptors 33.0

Rotatable Bonds 66.0

Heavy Atoms 151.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0376220 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/