Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC350H573N105O89S8

DescriptionStandard

        MKIHLFFLILLFCVTILPARKRYPEYGSLDLRRECKRSNGRCKNQCLETEIRIAFCIRPGTRCCIHS
    

Molecular Weight7932.46 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.61

Net Charge (pH 7.4) 7.18

Charge Density (pH 7.0) 0.1136

GRAVY Index-0.05

Hydrophobic Moment 0.62

Boman Index-0.09

Instability Index63.43

Aliphatic Index 94.63

Aromaticity 0.0896

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3153.70

LogP -25.79

H-bond Donors 121.0

H-bond Acceptors 107.0

Rotatable Bonds 266.0

Heavy Atoms 552.0

Ring Count 11.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066836 VERIFIED: NO

Provenance & Taxonomy

OrganismIctidomys tridecemlineatus [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence