Peptide Database

Peptide NameThymopentin + 6R, RR-11

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC66H121N33O15

DescriptionStandard

        RKDVYRRRRRR
    

Molecular Weight1616.88 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.6145

GRAVY Index-3.27

Hydrophobic Moment 0.17

Boman Index-1.71

Instability Index247.23

Aliphatic Index 26.36

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 871.17

LogP -9.70

H-bond Donors 36.0

H-bond Acceptors 22.0

Rotatable Bonds 58.0

Heavy Atoms 114.0

Ring Count 1.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0099766 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetMycobacterium smegmatis ATCC 14468

Activity125 μg/mL

MethodMIC

RECORD: Rec_0153634 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic designed peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antimycobacterial Immunomodulatory

TargetMycobacterium smegmatis RIF-susceptible

Activity125 μg/mL

MethodMIC

RECORD: Rec_0221992 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetRat erythrocytes

Activity>2000 μg/mL

MethodHemolysis

RECORD: Rec_0350304 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic designed peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antimycobacterial Immunomodulatory

TargetMycobacterium smegmatis RIF-Resistance

Activity125 μg/mL

MethodMIC