Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC184H332N70O50S6

DescriptionStandard

        ALQKVHCKIRKGRCALRSCLAKEEQIGNCSRNRKCCRKK
    

Molecular Weight4517.43 Da

Isoelectric Point (pI)10.19

Net Charge (pH 7.0)10.82

Net Charge (pH 7.4) 10.48

Charge Density (pH 7.0) 0.2775

GRAVY Index-0.92

Hydrophobic Moment 0.70

Boman Index-0.50

Instability Index59.56

Aliphatic Index 65.13

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2038.76

LogP -24.95

H-bond Donors 80.0

H-bond Acceptors 68.0

Rotatable Bonds 166.0

Heavy Atoms 310.0

Ring Count 1.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071530 VERIFIED: YES

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)