Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC367H589N103O100S7

DescriptionStandard

        VRIAVLLFTIFFFMSQVLPAGGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLGHQPRIESTTLKKD
    

Molecular Weight8268.69 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.86

Net Charge (pH 7.4) 2.45

Charge Density (pH 7.0) 0.0392

GRAVY Index0.05

Hydrophobic Moment 0.50

Boman Index0.02

Instability Index57.58

Aliphatic Index 88.08

Aromaticity 0.0822

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3242.71

LogP -28.88

H-bond Donors 118.0

H-bond Acceptors 112.0

Rotatable Bonds 272.0

Heavy Atoms 577.0

Ring Count 13.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081736 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Bacterium]

FamilyDefensin

Tax ID9601

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence