Peptide Database

Peptide NameSLAY-screened peptide P4507

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC103H167N29O28S4

DescriptionStandard

        SCKTMLNHKLMDHITSLFMH
    

Molecular Weight2387.87 Da

Isoelectric Point (pI)7.99

Net Charge (pH 7.0)0.71

Net Charge (pH 7.4) 0.33

Charge Density (pH 7.0) 0.0355

GRAVY Index-0.03

Hydrophobic Moment 0.58

Boman Index0.08

Instability Index84.00

Aliphatic Index 78.00

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 915.61

LogP -7.52

H-bond Donors 33.0

H-bond Acceptors 36.0

Rotatable Bonds 81.0

Heavy Atoms 164.0

Ring Count 4.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0233196 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/