Peptide Database

Peptide NameexnP signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC118H188N30O30S2

DescriptionStandard

        MNNNKLLLVDGMALLFRAFFATA
    

Molecular Weight2571.07 Da

Isoelectric Point (pI)8.50

Net Charge (pH 7.0)0.50

Net Charge (pH 7.4) 0.28

Charge Density (pH 7.0) 0.0218

GRAVY Index0.83

Hydrophobic Moment 0.50

Boman Index0.30

Instability Index15.00

Aliphatic Index 114.78

Aromaticity 0.1304

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 978.24

LogP -6.23

H-bond Donors 33.0

H-bond Acceptors 33.0

Rotatable Bonds 85.0

Heavy Atoms 180.0

Ring Count 3.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0021171 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

Activity0.0 U/mL

MethodCutinase activity assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/