Peptide Database

Peptide NameD-Nal,Cys,Tyr,D-Trp,Orn,Val,Cys,Nal-NH2

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC43H62N12O10S2

DescriptionStandard

        ACYWRVCA
    

Molecular Weight971.16 Da

Isoelectric Point (pI)8.10

Net Charge (pH 7.0)0.78

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0969

GRAVY Index0.76

Hydrophobic Moment 0.31

Boman Index0.18

Instability Index50.71

Aliphatic Index 61.25

Aromaticity 0.2500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 364.94

LogP -1.72

H-bond Donors 16.0

H-bond Acceptors 13.0

Rotatable Bonds 26.0

Heavy Atoms 67.0

Ring Count 3.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0093427 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetBB1 receptor (Human); BB2 receptor (Human)

Activity468-630 nM

MethodIC50