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MYP_121503
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Basic Information
PreS2 3S Mutant
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C46H77N15O21
Standard
Sequence
PSSSSSSRIGDP
Physicochemical Analysis
1176.19 Da
6.27
-0.04
-0.10
-0.0034
-0.99
0.36
-0.20
121.52
32.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
581.22
-11.97
22.0
21.0
36.0
82.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031285 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
EGFP
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID10822301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822301/
RECORD: Rec_0039223 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
EGFP
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID10822301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822301/
RECORD: Rec_0077866 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Conjugated with EGFP
None
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0230005 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
PreS2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
EGFP fusion
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID10822301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822301/
RECORD: Rec_0267096 VERIFIED: YES
Provenance & Taxonomy
Hepatitis B virus [Virus]
Protein-derived CPP
10407
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Conjugated with EGFP
None
N-term detail: Conjugated with EGFP
Bio-Activity Profile
Cell-penetrating peptide
HepG2; HeLa; 293 cells
Cellular uptake assay
PMID10822301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822301/
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