Peptide Database

Peptide NamePantinin-3 (Non-disulfide-bridged peptide 4.22) (NDBP-4.22) (Non-disulfide-bridged peptide 5.23) (NDBP-5.23)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC349H559N85O104S2

DescriptionStandard

        MKTQFAILLIALVLFQLLSQSDAFLSTIWNGIKSLLGRRGLNELDNLDELFDGEISQADIDFLKELMS
    

Molecular Weight7673.81 Da

Isoelectric Point (pI)4.24

Net Charge (pH 7.0)-5.48

Net Charge (pH 7.4) -5.72

Charge Density (pH 7.0) -0.0807

GRAVY Index0.36

Hydrophobic Moment 0.72

Boman Index0.19

Instability Index33.27

Aliphatic Index 130.59

Aromaticity 0.0882

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3067.14

LogP -22.82

H-bond Donors 104.0

H-bond Acceptors 101.0

Rotatable Bonds 266.0

Heavy Atoms 540.0

Ring Count 7.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017141 VERIFIED: YES

Provenance & Taxonomy

OrganismPandinus imperator [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0042927 VERIFIED: YES

Provenance & Taxonomy

OrganismPandinus imperator [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEnterococcus spp.

RECORD: Rec_0187314 VERIFIED: YES

Provenance & Taxonomy

OrganismPandinus imperator [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEnterobacter cloacae

RECORD: Rec_0188713 VERIFIED: YES

Provenance & Taxonomy

OrganismPandinus imperator [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEscherichia coli

RECORD: Rec_0203989 VERIFIED: YES

Provenance & Taxonomy

OrganismPandinus imperator [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetBacillus megaterium

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