Peptide Database

Peptide NameBeta-defensin 110

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC354H523N87O87S7

DescriptionStandard

        MKIHLFFFILLFWVTILPARSNFDPKYRFERCAKVKGICKTFCDDDEYDYGYCIKWRNQCCI
    

Molecular Weight7613.93 Da

Isoelectric Point (pI)8.58

Net Charge (pH 7.0)2.53

Net Charge (pH 7.4) 2.15

Charge Density (pH 7.0) 0.0408

GRAVY Index-0.03

Hydrophobic Moment 0.53

Boman Index0.04

Instability Index23.87

Aliphatic Index 75.48

Aromaticity 0.2097

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2816.80

LogP -14.00

H-bond Donors 105.0

H-bond Acceptors 98.0

Rotatable Bonds 246.0

Heavy Atoms 535.0

Ring Count 18.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109269 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KU3/entry; https://bblserver.org.in/ampdb/