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MYP_121481
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
5 amino acids
C24H42N6O9
Standard
Sequence
VVNDL
Physicochemical Analysis
558.62 Da
4.05
-1.26
-1.48
-0.2530
1.04
0.69
0.31
8.00
194.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
260.11
-1.95
8.0
8.0
17.0
39.0
0.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0142208 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 20.0%, C 80.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0156694 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
None
Bio-Activity Profile
Antimicrobial Antiviral
Herpes simplex virus type 1:inhibition of HSV-1 ribonucleotide reductase activity
400 μM
IC50
PaperPubMed PMID: 3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0203039 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Herpes simplex virus type 1:inhibition of HSV-1 ribonucleotide reductase activity
760 μM
IC50
PaperPubMed PMID: 3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0332660 VERIFIED: YES
Provenance & Taxonomy
Human alphaherpesvirus 1 [Virus]
Virus-derived peptide
10298;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Herpes simplex virus 1 (Replication); BHK-21/C
760 μM
Ribonucleotide reductase assay
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase. | Gaudreau P, Michaud J, Cohen EA, Langelier Y, Brazeau P. | J Biol Chem. 1987 | PMID:3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0333170 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
None
Bio-Activity Profile
Antiviral
Herpes simplex virus type 1
400 μM
IC50
Mammalian: 100 h; Yeast: >20 h; E. coli: >10 h
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase. | Gaudreau P, Michaud J, Cohen EA, Langelier Y, Brazeau P. | J Biol Chem. 1987 Sep 15;262(26):12413-6. | DOI:Not available | PMID:3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
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