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MYP_121481
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Basic Information
H2-(11-15)
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
5 amino acids
C24H42N6O9
Standard
Sequence
VVNDL
Physicochemical Analysis
558.62 Da
4.05
-1.26
-1.48
-0.2530
1.04
0.69
0.31
8.00
194.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
260.11
-1.95
8.0
8.0
17.0
39.0
0.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0142208 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Enzyme inhibitor HSV-1 replication inhibitor
HSV-1 ribonucleotide reductase
760 μM
IC50 (ribonucleotide reductase enzyme-inhibition assay)
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase PMID24285301;3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0156694 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
None
Bio-Activity Profile
Antiviral Enzyme inhibitor HSV-1 replication inhibitor
HSV-1 ribonucleotide reductase
400 μM
IC50 (ribonucleotide reductase enzyme-inhibition assay)
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0203039 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Enzyme inhibitor HSV-1 replication inhibitor
HSV-1 ribonucleotide reductase
760 μM
IC50 (ribonucleotide reductase enzyme-inhibition assay)
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0332660 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Virus-derived peptide
10298;0
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
Antiviral Enzyme inhibitor HSV-1 replication inhibitor
HSV-1 ribonucleotide reductase
760 μM
IC50 (ribonucleotide reductase enzyme-inhibition assay)
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0333170 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
None
Bio-Activity Profile
Antiviral Enzyme inhibitor HSV-1 replication inhibitor
HSV-1 ribonucleotide reductase
400 μM
IC50 (ribonucleotide reductase enzyme-inhibition assay)
Mammalian: 100 h; Yeast: >20 h; E. coli: >10 h
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
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