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MYP_121470
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Basic Information
BMAP-27
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C158H262N44O28
Standard
Sequence
GRFKRFRKKFKKLFKKLSPVIPLLHL
Physicochemical Analysis
3226.05 Da
12.00
9.84
9.58
0.3785
-0.37
0.82
-0.21
21.48
101.15
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1189.99
-3.28
43.0
39.0
113.0
230.0
7.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032707 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Cathelicidin
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Staphylococcus aureus
2.481 μM
Crystal violet assay
PaperAntibacterial and anti-biofilm effects of cathelicidin peptides against pathogens isolated from cystic fibrosis patients PMID21849157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849157/
RECORD: Rec_0062240 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Anticancer
PMID31226350 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31226350/
RECORD: Rec_0065747 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
6.2 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21497177/ PMID21497177 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21497177/
RECORD: Rec_0087811 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID31226350 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31226350/
RECORD: Rec_0093339 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Cathelicidin
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Stenotrophomonas maltophilia
2.481, 4.963 μM
Total countable CFUs
PaperAntibacterial and anti-biofilm effects of cathelicidin peptides against pathogens isolated from cystic fibrosis patients PMID21849157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849157/
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