Peptide Database

Peptide NameUnnamed

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC43H54N12O8

DescriptionStandard

        WWPKHGG
    

Molecular Weight866.96 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.1209

GRAVY Index-1.61

Hydrophobic Moment 0.29

Boman Index0.11

Instability Index11.39

Aliphatic Index 0.00

Aromaticity 0.2857

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 315.41

LogP -0.38

H-bond Donors 11.0

H-bond Acceptors 10.0

Rotatable Bonds 22.0

Heavy Atoms 63.0

Ring Count 6.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219245 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid

Targetmu opioid receptor

Activity0.01 μM

MethodIC50

PaperDooley C.T., Kaplan R.A., Chung N.N., Schiller P.W., Bidlack J.M., Houghten R.A.. Six highly active mu-selective opioid peptides identified from two synthetic combinatorial libraries. Peptide Research, 8, 3, 124-137(1995). PMID7670227 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7670227/

RECORD: Rec_0369660 VERIFIED: NO