Peptide Database

Peptide NameAurein-1.2 [D5K,A10W,E11K]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC82H130N18O15

DescriptionStandard

        GLFKIIKKIWKSF
    

Molecular Weight1608.02 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2889

GRAVY Index0.40

Hydrophobic Moment 0.84

Boman Index0.21

Instability Index-21.92

Aliphatic Index 120.00

Aromaticity 0.2308

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 552.62

LogP 0.75

H-bond Donors 20.0

H-bond Acceptors 19.0

Rotatable Bonds 56.0

Heavy Atoms 115.0

Ring Count 4.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096462 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAurein

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 29213

Activity3.12 μg/mL

MethodMIC

RECORD: Rec_0206297 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAurein

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHuman erythrocytes (5% Hemolysis at 25 microg/ml

Activity25 μg/mL

MethodHemolysis