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MYP_121452
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Basic Information
22A-30R-NH2 fragment 4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C51H90N18O11
Standard
Sequence
ALYLAIRRR
Physicochemical Analysis
1131.37 Da
11.71
2.79
2.61
0.3105
0.10
0.26
-0.29
136.18
152.22
0.1111
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
502.05
-2.81
20.0
14.0
37.0
80.0
1.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0258637 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
3 μg/mL
MIC
PMID9931294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9931294/
RECORD: Rec_0273756 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus (MRSA)
24 μg/mL
MIC
PMID9931294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9931294/
RECORD: Rec_0294324 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 33.3%, E 0.0%, T 22.2%, C 44.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0303904 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19154767/
RECORD: Rec_0358042 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiparasitic Antitrypanosomal
Trypanosoma brucei brucei GUTat3.1
Cell numbers counted by Z1 Coulter Counter
PMID19584534 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
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