Peptide Database

Peptide NameEsculentin-2MT3

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC372H612N102O109S5

DescriptionStandard

        MFTLKKSMLLLFFLGTISLSLCEEERNADEDDGEKEVKRGIFALIKTAAKFVGKNLLRQAGKAGLEHLACKANNQC
    

Molecular Weight8417.78 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)1.57

Net Charge (pH 7.4) 1.23

Charge Density (pH 7.0) 0.0207

GRAVY Index-0.10

Hydrophobic Moment 0.72

Boman Index0.00

Instability Index23.34

Aliphatic Index 95.13

Aromaticity 0.0658

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3447.30

LogP -31.24

H-bond Donors 121.0

H-bond Acceptors 117.0

Rotatable Bonds 299.0

Heavy Atoms 588.0

Ring Count 6.0

Amide Bonds 81.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0355531 VERIFIED: NO

Provenance & Taxonomy

OrganismAmolops mantzorum [Animal]

FamilyFrog skin active peptide (FSAP)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence