Peptide Database

Peptide NamedCATH 12 (modified from dCATH)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC74H124N24O14

DescriptionStandard

        LAIKIYRAWKRR
    

Molecular Weight1573.93 Da

Isoelectric Point (pI)11.73

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.3964

GRAVY Index-0.59

Hydrophobic Moment 0.75

Boman Index-0.37

Instability Index55.83

Aliphatic Index 114.17

Aromaticity 0.1667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 657.18

LogP -2.37

H-bond Donors 26.0

H-bond Acceptors 19.0

Rotatable Bonds 53.0

Heavy Atoms 112.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0356207 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive

TargetVREF ATCC 51559

Activity32 μM

MethodMIC

RECORD: Rec_0424337 VERIFIED: YES