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MYP_121393
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Basic Information
Unnamed
Antiviral
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Immune modulation ▸ Immunostimulatory activity
Immunology ▸ Immunomodulation ▸ Immunoregulator
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Standard
3 amino acids
C21H33N3O5
Standard
Sequence
LLY
Physicochemical Analysis
407.50 Da
5.52
-0.24
-0.45
-0.0803
2.10
0.38
0.79
6.67
260.00
0.3333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
141.75
1.41
5.0
5.0
11.0
29.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0260420 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunostimulatory
PaperBerthou J., Migliore-Samour D., Lifchitz A., Delettre J., Floc'h F., Jolles P.. Immunostimulating properties and three-dimensional structure of two tripeptides from human and cow caseins. FEBS Lett., 146, 79-87, 1987.
RECORD: Rec_0359809 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
99130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
SARS-CoV-2 main protease
PaperViral 3CLpro as a target for antiviral intervention using milk-derived bioactive peptides. International Journal of Peptide Research and Therapeutics 27:2703-2716 (2021). PMID: 34548852. PMID34548852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34548852/
RECORD: Rec_0365547 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Amaranthus hypochondriacus [Plant]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunoregulator
RECORD: Rec_0367249 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Anti-inflammatory Macrophage-modulating
Caco-2 cells
Cell proliferation assay
PaperBio-accessible milk casein-derived tripeptide (LLY) mediates overlapping anti- inflammatory and anti-oxidative effects under cellular (Caco-2) and in vivo milieu | Kandukuri, S. et al. | DOI: 10.1016/j.jnutbio.2018.09.002 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
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