Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC785H1238N230O233S4

DescriptionStandard

        MEINNQRKAFLDMLAWSEGTDNGRQKTRNHGYDVIVGGELFTDYSDHPRKLVTLNPKLKSTAAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKERGALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIEV
    

Molecular Weight17753.89 Da

Isoelectric Point (pI)9.21

Net Charge (pH 7.0)3.77

Net Charge (pH 7.4) 3.34

Charge Density (pH 7.0) 0.0240

GRAVY Index-0.65

Hydrophobic Moment 0.68

Boman Index-0.12

Instability Index26.15

Aliphatic Index 77.13

Aromaticity 0.0892

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7560.16

LogP -76.21

H-bond Donors 264.0

H-bond Acceptors 244.0

Rotatable Bonds 602.0

Heavy Atoms 1252.0

Ring Count 26.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107411 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage phiv205-1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic

RECORD: Rec_0141579 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica subsp. enterica serovar Montevideo str. S5-403 [Bacterium]

FamilyGlycosyl hydrolase 24

Tax ID28901

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic Non-ribosomal

MethodQualitative functional evidence