Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC459H721N127O137S13

DescriptionStandard

        LPDGDFIIQGCPECKLKENKYFSKGGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKSFTKATVMGNARVENHTECHCSTCYYHKS
    

Molecular Weight10627.25 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)5.92

Net Charge (pH 7.4) 5.39

Charge Density (pH 7.0) 0.0617

GRAVY Index-0.38

Hydrophobic Moment 0.62

Boman Index-0.04

Instability Index54.58

Aliphatic Index 47.81

Aromaticity 0.0938

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4231.26

LogP -48.09

H-bond Donors 156.0

H-bond Acceptors 159.0

Rotatable Bonds 346.0

Heavy Atoms 736.0

Ring Count 18.0

Amide Bonds 101.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0102880 VERIFIED: YES

Provenance & Taxonomy

OrganismMeriones unguiculatus [Animal]

FamilyGlycoprotein hormones

Tax ID10047

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-86; 36-88; 63-91

Other Mods56:N-linked (GlcNAc...) asparagine; 82:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min