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MYP_121364
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
12 amino acids
C51H81N13O20
Standard
Sequence
STSYAGAVVNDL
Physicochemical Analysis
1196.26 Da
4.05
-1.54
-1.75
-0.1283
0.40
0.32
0.26
21.82
97.50
0.0833
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
544.73
-7.58
19.0
19.0
36.0
84.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0072927 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US4795740A/en PatentUS 4795740 A
RECORD: Rec_0147696 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0382269 VERIFIED: YES
Provenance & Taxonomy
Human alphaherpesvirus 1 [Virus]
Virus-derived peptide
10298;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Herpes simplex virus 1 (Replication); BHK-21/C
29 μM
Ribonucleotide reductase assay
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase. | Gaudreau P, Michaud J, Cohen EA, Langelier Y, Brazeau P. | J Biol Chem. 1987 | PMID:3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0410715 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral
Herpes simplex virus type 1
29 μM
IC50
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase. | Gaudreau P, Michaud J, Cohen EA, Langelier Y, Brazeau P. | J Biol Chem. 1987 Sep 15;262(26):12413-6. | DOI:Not available | PMID:3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/