Peptide Database

Peptide NamePancrelipase

Function Ontology

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length239 amino acids

Chemical FormulaC1194H1806N336O354S13

DescriptionStandard

        PANCREATICQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAGSKPF
    

Molecular Weight26948.00 Da

Isoelectric Point (pI)6.61

Net Charge (pH 7.0)-0.67

Net Charge (pH 7.4) -1.17

Charge Density (pH 7.0) -0.0028

GRAVY Index-0.46

Hydrophobic Moment 0.61

Boman Index-0.02

Instability Index31.32

Aliphatic Index 68.54

Aromaticity 0.1172

Extinction Coeff. Reduced 54890.00

Extinction Coeff. Oxidized 55390.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0241511 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]; Sus scrofa [Animal]

FamilyEnzyme

Tax ID9913;9823

Structure & Mods

Configheterogeneous macromolecular preparation [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Enzyme replacement

Half-LifePancrelipase is not significantly absorbed from the gastrointestinal tract and acts locally, so there is no terminal elimination half life.

PaperPubMed-linked source references: PMID:28099252; PMID:27560634; PMID:26748629; PMID:26726093; PMID:26709820; PMID:26495784; PMID:26495776; PMID:26150571; PMID:26036459 PMID28099252;27560634;26748629;26726093;26709820;26495784;26495776;26150571;26036459 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28099252/