MYP_121330
Basic Information
Rugosin-B
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antibiotic activity
Immunology Innate immune defense Host defense peptide Defense peptide
Toxicity / Safety Negative safety assay result Non-hemolytic
Standard
33 amino acids
C159H264N42O43S2
Standard
Sequence
SLFSLIKAGAKFLGKNLLKQGAQYAACKVSKEC
Physicochemical Analysis
3516.18 Da
9.70
4.44
4.19
0.1344
0.15
0.60
0.08
32.95
94.85
0.0909
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1398.13
-12.85
50.0
50.0
124.0
246.0
3.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0405996 VERIFIED: YES
Provenance & Taxonomy
Glandirana rugosa [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO-1
100 μg/mL
MIC
RECORD: Rec_0412925 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial
Micrococcus luteus ATCC 934
1.56 μg/mL
MIC
RECORD: Rec_0419595 VERIFIED: YES
Provenance & Taxonomy
Glandirana rugosa [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pyogenes COOK
12.5 μg/mL
MIC
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