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MYP_121314
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Basic Information
LSer-Def7
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
32 amino acids
C146H239N49O42S6
Standard
Sequence
FTCNSYACKAHCILQGHKSGSCARINLCKCQR
Physicochemical Analysis
3545.15 Da
9.15
4.87
4.47
0.1522
-0.20
0.39
-0.10
59.60
58.12
0.0625
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1498.15
-19.81
59.0
55.0
119.0
243.0
4.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013574 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
LSer
13632
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperAntimicrob Agents Chemother. 2015 May;59(5):2508-14 | http://www.ncbi.nlm.nih.gov/pubmed/25666157 PMID25666157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25666157/
RECORD: Rec_0069550 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
100 μM
MIC
PMID25666157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25666157/
RECORD: Rec_0160011 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
100 μM
MIC
RECORD: Rec_0164956 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
51.1 μM
MIC
RECORD: Rec_0178196 VERIFIED: YES
Provenance & Taxonomy
Temnothorax curvispinosus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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