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MYP_121288
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Basic Information
Cy-AMP1 (Plant defensin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
44 amino acids
C198H298N52O58S8
Standard
Sequence
KGAPCAKKPCCGPLGHYKVDCSTIPDYPCCSKYGFCGSGPQYCG
Physicochemical Analysis
4591.32 Da
8.47
2.76
2.38
0.0628
-0.34
0.37
0.05
9.25
28.86
0.1136
5960.00
6460.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1700.19
-19.85
64.0
70.0
137.0
316.0
12.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0401660 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Fusarium oxysporum f. sp. cucumerium
6 μg/mL
IC50
PaperPubMed PMID 18778743 | PubMed PMID 19466690 | Tokoyama et al 2009 J Pept Sci 15: 492-7 PMID18778743;19466690 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18778743/
RECORD: Rec_0402461 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Clavibacter michiganensis subsp. michiganensis
7.3 μg/mL
IC50
PaperPubMed PMID 18778743 | PubMed PMID 19466690 | Tokoyama et al 2009 J Pept Sci 15: 492-7 PMID18778743;19466690 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18778743/
RECORD: Rec_0417355 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Gram negative bactera at
7000-8900 μg/mL
IC50
RECORD: Rec_0421592 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
G. candidum
7.4 μg/mL
IC50
PaperPurification, characterization, and sequencing of antimicrobial peptides, Cy-AMP1, Cy-AMP2, and Cy-AMP3, from the Cycad (Cycas revoluta) seeds
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