Peptide Database

Peptide NameUrotensin II

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC63H88N14O19S2

DescriptionStandard

        GSTSECFWKYCV
    

Molecular Weight1409.59 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-0.26

Net Charge (pH 7.4) -0.50

Charge Density (pH 7.0) -0.0216

GRAVY Index-0.03

Hydrophobic Moment 0.31

Boman Index0.15

Instability Index55.55

Aliphatic Index 24.17

Aromaticity 0.2500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 543.45

LogP -4.85

H-bond Donors 22.0

H-bond Acceptors 21.0

Rotatable Bonds 42.0

Heavy Atoms 98.0

Ring Count 4.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085659 VERIFIED: NO

Provenance & Taxonomy

OrganismAcipenser ruthenus [Animal] [Animal]; Polyodon spathula [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0093708 VERIFIED: YES

Provenance & Taxonomy

OrganismPolyodon spathula [Animal]

FamilyUrotensin

Tax ID7913

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation

Targetsmooth muscle

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour