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MYP_121280
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Basic Information
Fibrinopeptide A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Hemostasis ▸ Coagulation regulation
Standard
16 amino acids
C63H97N19O26
Standard
Sequence
ADSGEGDFLAEGGGVR
Physicochemical Analysis
1536.56 Da
4.05
-3.20
-3.39
-0.1998
-0.43
0.21
0.06
22.11
55.00
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
731.15
-10.25
25.0
23.0
51.0
108.0
1.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0347895 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Penicillium expansum
42-84 μM
MIC
PMID30425969 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30425969/
RECORD: Rec_0354182 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 6743769 B1 Evidence URLhttps://patents.google.com/patent/US6743769B1/en PatentUS 6743769 B1
RECORD: Rec_0383590 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Paecilomyces farinosus IBCB-215
42-84 μM
MIC
PMID30425969 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30425969/
RECORD: Rec_0398165 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
DAT-FPA was labeled with 125-iodine or with 123-iodine by chloramine-T
Bio-Activity Profile
Blood clotting
Gel filtration chromatography of blood plasma at different time interval show that rapid clearence of peptide from blood plasma.
Intravenous injection in lateral vein of nephrectomized rabbits, in vivo; 420 s
PMID6658706 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6658706/
RECORD: Rec_0413853 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Blood clotting
Gel filtration chromatography of blood plasma at different time interval show that rapid clearence of peptide from blood plasma.
Intravenous injection in lateral vein of nephrectomized rabbits, in vivo; 240 s
PMID6658706 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6658706/
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