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MYP_121267
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Basic Information
C1b(3-12)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
10 amino acids
C77H100N26O11
Standard
Sequence
VWRHWRRFWH
Physicochemical Analysis
1565.79 Da
12.00
2.91
2.60
0.2908
-1.56
0.93
-0.37
106.34
29.00
0.4000
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
615.65
-0.45
25.0
16.0
44.0
114.0
9.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0208564 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa CGMCC 1.860
12.5 μM
MIC
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0347094 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis CGMCC 1.595
12.5 μM
MIC
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0347704 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (- at NA
Hemolysis
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0349273 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus
6.25 μM
MIC
PaperStructure-activity analysis and biological studies of chensinin-1b analogues. Acta Biomater. 2016 Jun;37:59-68. doi: 10.1016/j.actbio.2016.04.003. PMID: 27060618. PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0365073 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
500 μM
HC50
PaperStructure-activity analysis and biological studies of chensinin-1b analogues. Acta Biomater. 2016 Jun;37:59-68. doi: 10.1016/j.actbio.2016.04.003. PMID: 27060618. PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
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