Peptide Database

Peptide NameGalectin-3-binding peptide (f88-Cys6 clone)

Function Ontology

Anticancer

Anticancer ▸ Tumor Homing Peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC73H118N24O22S3

DescriptionStandard

        NISRCTHPFMACGKQS
    

Molecular Weight1780.06 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.54

Charge Density (pH 7.0) 0.1142

GRAVY Index-0.43

Hydrophobic Moment 0.45

Boman Index-0.09

Instability Index151.59

Aliphatic Index 30.62

Aromaticity 0.0625

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 754.50

LogP -10.41

H-bond Donors 28.0

H-bond Acceptors 28.0

Rotatable Bonds 57.0

Heavy Atoms 122.0

Ring Count 3.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238754 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic/phage-display construct [Synthetic]

Structure & Mods

Configdisulfide-constrained phage-display peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Galectin-3 binding Protein-binding Tumor-homing Metastasis-associated adhesion inhibition

Targetgalectin-3 carbohydrate recognition domain; MDA-MB-435 breast carcinoma/endothelial cell adhesion

MethodCombinatorial bacteriophage-display binding selection; cell-adhesion inhibition assay

RECORD: Rec_0382161 VERIFIED: YES