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MYP_121222
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Basic Information
Crabrolin (Insects, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C74H129N17O15
Standard
Sequence
FLPLILRKIVTAL
Physicochemical Analysis
1496.92 Da
11.00
1.76
1.55
0.1353
1.72
0.54
0.46
34.08
210.00
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
511.88
0.69
18.0
17.0
48.0
106.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0201337 VERIFIED: YES
Provenance & Taxonomy
Vespa crabro [Animal]
MCD; Crabrolin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Cytolytic Hemolytic
PMID6206053;9273892 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6206053/
RECORD: Rec_0217654 VERIFIED: YES
Provenance & Taxonomy
Vespa crabro [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PMID9273892 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9273892/
RECORD: Rec_0310886 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Toxic Hemolytic Mast cell degranulation
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0333431 VERIFIED: YES
Provenance & Taxonomy
European hornet [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID7916722 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7916722/
RECORD: Rec_0345779 VERIFIED: YES
Provenance & Taxonomy
European hornet [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
PC-3
32.13 μM
IC50
PaperIsolation and characterization of two new peptides, mastoparan C and crabrolin, from the venom of the European hornet, Vespa crabro.
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Showing 5 records on this page · Page 4 of 6