MYP_121222
Basic Information
Crabrolin (Insects, animals)
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Hormonal / Endocrine Hormone peptide
Immunology Innate immune modulation Mast cell modulation
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytolysis / cell lysis Cytolytic activity
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
Standard
13 amino acids
C74H129N17O15
Standard
Sequence
FLPLILRKIVTAL
Physicochemical Analysis
1496.92 Da
11.00
1.76
1.55
0.1353
1.72
0.54
0.46
34.08
210.00
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
511.88
0.69
18.0
17.0
48.0
106.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0133683 VERIFIED: YES
Provenance & Taxonomy
European hornet [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
U251MG
20.13 μM
IC50
RECORD: Rec_0144346 VERIFIED: YES
Provenance & Taxonomy
European hornet [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
HaCaT
31.23 μM
IC50
RECORD: Rec_0144644 VERIFIED: YES
Provenance & Taxonomy
European hornet [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus aureus NCTC 10788 or MRSA
2-4 μM
MIC
RECORD: Rec_0147659 VERIFIED: YES
Provenance & Taxonomy
European hornet [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
HCT-116
8.539 μM
IC50
RECORD: Rec_0155110 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 53.8%, E 0.0%, T 23.1%, C 23.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
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