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MYP_121173
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Basic Information
hBDconsensus
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
32 amino acids
C154H260N54O42S6
Standard
Sequence
KKCWNGGRCRKKCKENEKPIGYCRNGKKCCVN
Physicochemical Analysis
3732.44 Da
9.70
8.70
8.39
0.2718
-1.48
0.45
-0.53
9.24
21.25
0.0625
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1633.47
-19.53
63.0
57.0
133.0
256.0
4.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017406 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
25 μM
MIC
PaperAntimicrobial activity and structure of a consensus human beta-defensin and its comparison to a novel putative hBD10
RECORD: Rec_0079924 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
M tuberculosis MDR
25.9 μM
MIC
PMID31325337 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31325337/
RECORD: Rec_0083381 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
12.5 μM
MIC
PaperAntimicrobial activity and structure of a consensus human beta-defensin and its comparison to a novel putative hBD10
RECORD: Rec_0131214 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
M tuberculosis H37Rv
8.8±3.3 μM
MIC
PMID31325337 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31325337/
RECORD: Rec_0152641 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBCs [Hemolysis % = 1.6]
Hemolysis
PMID31325337 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31325337/
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