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MYP_121163
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Basic Information
Proline-rich antimicrobial peptide 1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
37 amino acids
C195H306N60O52
Standard
Sequence
DIQIPGIKKPTHRDIIIPNWNPNVRTQPWQRFGGNKS
Physicochemical Analysis
4322.89 Da
11.00
3.85
3.59
0.1040
-1.06
0.45
-0.16
11.13
71.08
0.0811
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1827.91
-17.96
60.0
57.0
137.0
307.0
11.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0149708 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic
S. pombe
PMID11995991;17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11995991/
RECORD: Rec_0158744 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Micrococcus luteus
55 μM
MIC
PMID11995991;17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11995991/
RECORD: Rec_0168362 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Gm
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
PaperActa Biochim Pol 2001; 48: 1191-1195 | http://www.ncbi.nlm.nih.gov/pubmed/11995991 PMID11995991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11995991/
RECORD: Rec_0169206 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Schizosaccharomyces pombe
11 μM
MIC
PMID11995991;17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11995991/
RECORD: Rec_0187386 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
PrAMP
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
yeast-like fungi P. pastoris, Z. marxianus, C. wickerhamii
16.5 μM
MIC
PaperAntibacterial peptides of the moth Galleria mellonella
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