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MYP_121163
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Basic Information
Proline-rich antimicrobial peptide 1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
37 amino acids
C195H306N60O52
Standard
Sequence
DIQIPGIKKPTHRDIIIPNWNPNVRTQPWQRFGGNKS
Physicochemical Analysis
4322.89 Da
11.00
3.85
3.59
0.1040
-1.06
0.45
-0.16
11.13
71.08
0.0811
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1827.91
-17.96
60.0
57.0
137.0
307.0
11.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0077305 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0103860 VERIFIED: YES
Provenance & Taxonomy
Wax moth [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID14661954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14661954/
RECORD: Rec_0119084 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 10.8%, E 0.0%, T 54.1%, C 35.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0136771 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Listeria monocytogenes (Gram-positive)
PMID11995991;17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11995991/
RECORD: Rec_0145514 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
candida wickerhamii
16.5 μM
MIC
PMID11995991;17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11995991/
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