Peptide Database

Peptide NamePeptidoglycan recognition protein 1 (Peptidoglycan recognition protein short) (PGRP-S)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC923H1405N253O262S11

DescriptionStandard

        MLFAWAPFPALLGLADSCCFVVPRSEWKALPSECSKGLKKPVRYVVISHTAGSFCSSPDSCEQQARNVQLYQMKQLGWCDVAYNFLIGEDGHVYEGRGWTIKGDHTGPIWNPMSIGITFMGDYSHRVPAKRALRAALNLLKCGVSEGFLRSNYEVKGHRDVQSTLSPGDQLYEIIQSWDHYRE
    

Molecular Weight20590.28 Da

Isoelectric Point (pI)7.61

Net Charge (pH 7.0)0.98

Net Charge (pH 7.4) 0.31

Charge Density (pH 7.0) 0.0053

GRAVY Index-0.27

Hydrophobic Moment 0.81

Boman Index0.04

Instability Index51.66

Aliphatic Index 76.72

Aromaticity 0.1148

Extinction Coeff. Reduced 44920.00

Extinction Coeff. Oxidized 45295.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8209.86

LogP -85.75

H-bond Donors 292.0

H-bond Acceptors 280.0

Rotatable Bonds 664.0

Heavy Atoms 1449.0

Ring Count 43.0

Amide Bonds 195.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0318188 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-positive Chemotactic Cytotoxic Non-hemolytic

TargetGram-positive bacteria