Peptide Database

Peptide NamePN

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC114H173N27O43

DescriptionStandard

        SEQPDVDDYLRDVVLQSEEPLY
    

Molecular Weight2609.75 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-6.53

Net Charge (pH 7.4) -6.75

Charge Density (pH 7.0) -0.2968

GRAVY Index-0.88

Hydrophobic Moment 0.61

Boman Index-0.15

Instability Index101.42

Aliphatic Index 92.73

Aromaticity 0.0909

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1146.94

LogP -10.13

H-bond Donors 37.0

H-bond Acceptors 37.0

Rotatable Bonds 83.0

Heavy Atoms 184.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032604 VERIFIED: YES

Provenance & Taxonomy

OrganismLymnaea stagnalis [Animal]

FamilyPN

Tax ID6523

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Myotropic

Targeta number of significant neuron

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0146840 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0163695 VERIFIED: YES

Provenance & Taxonomy

OrganismLymnaea stagnalis [Animal]

FamilyPN

Tax ID6523

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Myotropic

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0318638 VERIFIED: NO

Provenance & Taxonomy

OrganismLymnaea stagnalis [Animal]

FamilyFMRFamide related peptide

Tax ID6523

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator