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MYP_121093
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Basic Information
WAM1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
36 amino acids
C199H345N63O41
Standard
Sequence
KRGFGKKLRKRLKKFRNSIKKRLKNFNVVIPIPLPG
Physicochemical Analysis
4276.27 Da
12.00
13.75
13.53
0.3820
-0.82
0.70
-0.35
31.09
91.94
0.0833
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1748.63
-12.76
62.0
55.0
153.0
303.0
6.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0306940 VERIFIED: YES
Provenance & Taxonomy
Macropus eugenii [Animal]
Cathelicidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 753
1.3 μM
MIC
PMID21912615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21912615/
RECORD: Rec_0319902 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0334707 VERIFIED: NO
Provenance & Taxonomy
Macropus eugenii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0368121 VERIFIED: YES
Provenance & Taxonomy
Macropus eugenii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Strep. pyogenes ATCC 19615
0.66 μM
MIC
PaperAncient antimicrobial peptides kill antibiotic-resistant pathogens: Australian mammals provide new options
RECORD: Rec_0384982 VERIFIED: YES
Provenance & Taxonomy
Macropus eugenii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
1.01 μM
MIC
PaperAncient antimicrobial peptides kill antibiotic-resistant pathogens: Australian mammals provide new options
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