Peptide Database

Peptide NameHepcidin 1a

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC444H706N130O136S13

DescriptionStandard

        MKCAHVALVAAVVIACVCILQTAAVPFVQQEQDEHQMEIETPQLNEHSTETTETQGQTNPLAFFRTKRQSHLSLCRYCCNCCRNKGCGYCCKF
    

Molecular Weight10457.99 Da

Isoelectric Point (pI)6.86

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.84

Charge Density (pH 7.0) -0.0026

GRAVY Index-0.15

Hydrophobic Moment 0.66

Boman Index-0.01

Instability Index50.77

Aliphatic Index 68.17

Aromaticity 0.0645

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4302.11

LogP -48.94

H-bond Donors 156.0

H-bond Acceptors 153.0

Rotatable Bonds 345.0

Heavy Atoms 723.0

Ring Count 13.0

Amide Bonds 105.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0290202 VERIFIED: NO

Provenance & Taxonomy

OrganismHypophthalmichthys nobilis [Animal]

FamilyHepcidin

Tax ID7965

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal